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Diminishing returns of ancestry analysis (for me)

Zack has finally started posting results from HAP. To the left you see the results generated at K = 5 from his merged data set with the first 10 HAP members. I am HRP002. Zack is HRP001. Paul G., who...

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Your genes, your rights – FDA’s Jeffrey Shuren misleading testimony under oath

Update: Welcome Instapundit readers! Please make sure to follow the very thorough discussion/debate over at Discover Blogs, where this has been cross-posted. End Update Over the past few days I’ve been...

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Income and IQ

As I noted in my recent post on Malcolm Gladwell’s Outliers, Gladwell ignored the possibility that traits with a genetic component, other than IQ, might play a role in determining success. His approach...

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The heritability debate, again

Like the level of selection debate, the debate about what heritability means has a life of its own. The latest shot comes from Scott Barry Kaufman who argues (among other things) that: The heritability...

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The miswired brain

Recent evidence indicates that psychiatric disorders can arise from differences, literally, in how the brain is wired during development. Psychiatric genetic approaches are finding new mutations...

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Where do morals come from?

Review of “Braintrust. What Neuroscience Tells Us about Morality”, by Patricia S. Churchland The question of “where morals come from” has exercised philosophers, theologians and many others for...

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Complex interactions among epilepsy genes

A debate has been raging over the last few years over the nature of the genetic architecture of so-called “complex” disorders. These are disorders – such as schizophrenia, epilepsy, type II diabetes...

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Environmental influences on autism – splashy headlines from dodgy data

A couple of recent papers have been making headlines in relation to autism, one claiming that it is caused less by genetics than previously believed and more by the environment and the other...

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Welcome to your genome

There is a common view that the human genome has two different parts – a “constant” part and a “variable” part. According to this view, the bases of DNA in the constant part are the same across all...

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Split brains, autism and schizophrenia

A new study suggests that a gene known to be causally linked to schizophrenia and other psychiatric disorders is involved in the formation of connections between the two hemispheres of the brain. DISC1...

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Does brain plasticity trump innateness?

The fact that the adult brain is very plastic is often held up as evidence against the idea that many psychological, cognitive or behavioural traits are innately determined. At first glance, there...

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De novo mutations in autism

A trio of papers in this week’s Nature identifies mutations causing autism in four new genes, demonstrate the importance of de novo mutations in the etiology of this disorder and suggest that there...

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